Side Effects of Seasonal Flu Vaccines
Flu Vaccine FluMist
Influenza Virus Vaccine Live, Intranasal
by Medimmune Vaccines, Inc.
Ingredients*: Chick Kidney Cells, Egg Protein, Gentamicin Sulfate, Monosodium Glutamate, Sucrose Phosphate Glutamate Buffer.
Published data** (including side effects, adverse effects, potential adverse effects, reactions, reports, experiences, observations or occurrences after vaccination and post marketing experience from Manufacturer Prescribing Information):
Wheezing, significant respiratory symptoms, hypersensitivity, including anaphylactic reaction, hospitalizations ("Most hospitalizations observed were gastrointestinal and respiratory tract infections and occurred more than 6 weeks post-vaccination." p.2 pp.17), runny nose, nasal congestion, decreased appetite, irritability, decreased activity (lethargy), sore throat, headache, muscle aches, chills, fever, sneezing, tiredness/weakness, cough, chills, sinusitis, exacerbation of symptoms of mitochondrial encephalomyopathy (Leigh syndrome), nausea, vomiting, diarrhea, anaphylactic reaction, facial edema and urticaria, Guillain-Barré syndrome, Bell's palsy, epistaxis, rash, herpes zoster [shingles].
Other Highlights: From the Manufacturer Prescribing Information***:
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"Do not administer FluMist to children <24 months of age because of increased risk of hospitalization and wheezing observed in clinical trials. (p.1 pp.6)
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"FluMist should not be administered to any individuals with asthma or children <5 years of age with recurrent wheezing because of the potential for increased risk of wheezing post-vaccination." (p.1 pp.6)
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FluMist has not been evaluated for its carcinogenic [cancer causing] or mutagenic [DNA altering] potential or its potential to impair fertility." (p.3 pp.16)
Flu Vaccine, FLUVIRIN®
(Flu) Influenza Virus Vaccine
by Chiron Vaccines Ltd. / Novartis
Ingredients*: Thimerosal [a preservative that is approximately 50% mercury by weight] (single dose and multidose), Beta-Propiolactone, Egg Protein, Neomycin, Polymyxin b, Polyoxyethylene 9-10 nonyl phenol (Triton N-101, Octoxynol 9).
Published data** (including side effects, adverse effects, potential adverse effects, reactions, reports, experiences, observations or occurrences after vaccination and post marketing experience from Manufacturer Prescribing Information):
Soreness, body aches, local pain and swelling, fever, malaise, myalgia, fever, irritability, Guillain-Barré syndrome, insomnia, seizure, erthema. [NOTE: There were no post-marketing adverse events offered on the prescribing instructions. However, there ere many safety statements that referred to a CDC/ACIP document with suggested guidelines for use – which is not the same as specific studies about this vaccine.]
Other Highlights: From the Manufacturer Prescribing Information***:
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“Animal reproduction studies have not been conducted with FLUVIRIN®. It is also not known whether FLUVIRIN® can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity." (p.3 pp.13).
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"The safety and immunogenicity of FLUVIRIN® have not been established in children <4 years of age." (p.3 pp.14)
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“Influenza virus is propagated in eggs for the preparation of influenza virus vaccine, thus, this vaccine should not be administered to anyone with a history of hypersensitivity [allergy] to chicken eggs, chicken, chicken feathers or chicken dander." (p.3 pp.8)
Flu Vaccine FLUZONE®
Influenza Virus Vaccine
by Sanofi Pasteur Inc.
Ingredients*: Thimerosal [a preservative that is approximately 50% mercury by weight], egg protein, formaldehyde or formalin, gelatin, octoxinol-9 (Triton X-100).
Published data** (including side effects, adverse effects, potential adverse effects, reactions, reports, experiences, observations or occurrences after vaccination and post marketing experience from Manufacturer Prescribing Information):
Guillain-Barré Syndrome (GBS), thrombocytopenia, lymphadenopathy, anaphylaxis, urticaria, angioedema, convulsions, myelitis (including encephalomyelitis and transverse myelitis), facial palsy (Bell's palsy), optic neuritis/neuropathy, brachial neuritis, syncope, (shortly after vaccination), dizziness, paresthesia, vasculitis, vasodilatation/flushing, dyspnea, pharyngitis, rhinitis, Stevens-Johnson syndrome, fever, pain, prurtis, asthenia/fatigue, pain in extremities, (related to egg allergy) chest pain, hives, angioedema, allergic asthma, systemic anaphylaxis. Neurological disorders temporally associated with influenza vaccination such as encephalopathy, optic neuritis/neuropathy, partial facial paralysis, and brachial plexus neuropathy have been reported.
Other Highlights: From the Manufacturer Prescribing Information***:
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"FLUZONE® vaccine has not been evaluated for carcinogenic [cancer causing] or mutagenic [DNA altering] potential, or for impairment of fertility." (p3. pp27.)
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Pediatric use: "The immune response and safety of FLUZONE vaccine was evaluated in 31 children between the ages of 6-26 months." (p.4 pp16.)
In : Medical Care
Tags: flu vaccine side effects risk vs benefit swine flu vaccine
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